What is Ketoconazole? Ketoconazole is an antibiotic belonging to the Azole Antifungal class of drugs, primarily used to inhibit the growth of fungi. While you might be surprised to see it mentioned in the context of steroid use, its benefits extend beyond treating infections.
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Ketoconazole has powerful anti-androgenic properties. It works by inhibiting androgen biosynthesis in both the adrenal glands and testes. This action reduces free testosterone levels in the blood, which in turn leads to a decrease in synthesized DHT (dihydrotestosterone). Ketoconazole is available in three common forms: oral, cream, and shampoo.
How It Helps With Hair Loss Steroids that are influenced by the 5-alpha reductase enzyme—such as testosterone and its DHT derivatives—can lead to androgenetic alopecia, or male pattern hair loss. This is where ketoconazole shampoo shines. It can block DHT receptors on the scalp, which helps to control hair loss and may even promote hair regrowth.
Common Uses
Ketoconazole shampoo is commonly used to treat a variety of conditions, including:
Ketoconazole shampoo is commonly used to treat a variety of conditions, including:
Scalp dermatitis
Fungal infectionsÂ
Eczema
Hirsutism in women (with or without PCOS)
Androgenetic alopecia (male pattern hair loss)Â