Tadalafil's Role in Performance and PCT - Featured image for article about steroid education
August 10, 20251 min

Tadalafil's Role in Performance and PCT

FitKolik

FitKolik

Published on August 10, 2025

Tadalafil, an effective medication for treating erectile dysfunction, offers a different set of benefits for athletes. Instead of being used for its traditional purpose, athletes use Tadalafil to enhance performance. Its mechanism involves increasing nitric oxide and inhibiting PDE-5, leading to significant vasodilation (widening of blood vessels) before a workout.

 
Tadalafil's anabolic potential goes further. It has been shown to:
 
*Increase insulin secretion 
*Decrease peripheral estradiol levels 
*Boost the expression of androgen receptors 
*Increase peripheral endogenous androgen levels 
 
These effects make it a powerful tool, especially during Post-Cycle Therapy (PCT). For PCT, taking 5 mg before your workout for 14 days is a recommended protocol. This can help increase the sensitivity of androgen receptors in muscle and myogenic cells, aiding in the restoration of your body's natural state and helping you maintain your gains.