Hormonal Balance: A Key to Cycle Success When on a cycle, it's easy to focus on testosterone and its immediate effects, but other hormones play a critical role in how your body responds. Two key players are thyroid hormones and estrogen.
An increase in either thyroid hormones or estrogen can lead to a rise in SHBG (Sex Hormone Binding Globulin). SHBG binds to free testosterone, making it unavailable to your body's androgen receptors. The result is a drop in your free testosterone levels, which can significantly reduce the effectiveness of your cycle.
For this reason, it's essential to closely monitor and maintain a balanced level of your T3, T4, and estradiol throughout your cycle. Keeping these hormones in check ensures that your free testosterone remains high, allowing you to get the most from the compounds you are using.