Growth Hormone's Impact on Hormonal Balance Growth hormone (GH), or Somatropin, is well-known for its anabolic properties, but its effects on other hormones are often overlooked.
When you inject GH, it increases the conversion of T4 to T3, which in turn lowers your T4 levels. In response, the pituitary gland attempts to compensate for this secondary hypothyroidism by increasing TSH secretion.
This chain reaction doesn't stop there. The hypothalamus is triggered to release TRH, which acts on the lactotroph cells in the pituitary to increase prolactin levels.
The resulting hormonal cascade can have significant consequences, including:
*Decreased testosterone and androgen receptors
*Increased estrogen and progesterone receptors
*The potential for gynecomastia
Understanding this complex interaction is crucial for anyone using Somatropin, as it highlights the importance of managing your overall hormonal balance to mitigate unwanted side effects like gynecomastia.