Winstrol (Stanozolol)

Active Substance: Winstrol

steroidoral

Description

Winstrol is the common brand name for the anabolic-androgenic steroid (AAS) Stanozolol.

Here is a detailed explanation based on your questions:

Winstrol (Stanozolol): Detail/Different Name

  • Chemical Name: Stanozolol

  • Brand Names (Common): Winstrol, Winstrol Depot (injectable), Stromba, Stanabol, Stanol, and others.

  • Classification: It is a synthetic derivative of dihydrotestosterone (DHT), a potent natural androgen.

  • Structure: Stanozolol is a 17-alpha-alkylated compound, meaning it has been chemically modified at the 17th carbon position to allow it to survive first-pass metabolism in the liver when taken orally. This modification, while making it orally active, also contributes to its liver toxicity (hepatotoxicity).

  • Forms: It is available in both oral tablets and an injectable, aqueous (water-based) suspension (Winstrol Depot).


Benefits (Pros) and Side Effects (Cons)

Category Benefits (Pros) - Primarily associated with performance/physique use Side Effects (Cons) - Risks associated with use
General Used medically to treat hereditary angioedema (HAE) by reducing the frequency and severity of attacks. Hepatotoxicity (Liver Toxicity): A major concern, especially with the oral form, leading to elevated liver enzymes, jaundice, and, rarely, liver tumors (hepatocellular neoplasms or peliosis hepatis).
Physique/Performance Enhanced Muscle Definition & Hardness: Helps achieve a 'dry' and 'chiseled' look due to its diuretic effect and lack of estrogen conversion. Cardiovascular Risks: Adversely affects cholesterol levels, significantly lowering HDL (good cholesterol) and raising LDL (bad cholesterol), increasing the risk of atherosclerosis, heart attack, and stroke.
Performance Increased Strength and Endurance: Often used in cutting cycles to help retain lean muscle mass while losing body fat and to boost strength. Androgenic Side Effects: Acne, oily skin, and potential accelerated hair loss (male pattern baldness) in genetically predisposed individuals.
Hormonal Minimal Estrogenic Effects: Does not convert to estrogen (non-aromatizable), meaning estrogen-related side effects like water retention/bloating and gynecomastia (male breast enlargement) are not a direct risk. Testosterone Suppression: Like most AAS, it suppresses natural testosterone production, requiring proper Post-Cycle Therapy (PCT) to restore hormonal balance.
Other Increases red blood cell production (erythropoiesis), which aids oxygen delivery to muscles. Virilization in Women: Irreversible side effects such as deepening of the voice, clitoral enlargement, and increased body/facial hair growth (hirsutism).
Other Reduces Sex Hormone-Binding Globulin (SHBG), potentially increasing the level of free, active hormones. Joint Pain: Some users report dry or painful joints, as it tends to reduce water retention, including in joint tissues.

Dosage and Frequency

Stanozolol is a controlled substance and is banned by major sports organizations (WADA). The following dosages reflect typical usage in performance-enhancing contexts, not medical recommendations. Dosage should only be determined by a qualified medical professional for approved therapeutic uses.

  • Oral (Tablets): Common doses for physique enhancement typically range from 25 mg to 50 mg per day. Due to its relatively short half-life and C17-alpha alkylation, oral doses are often split throughout the day (e.g., morning and evening) to maintain stable blood levels.

  • Injectable (Winstrol Depot): Common doses range from 50 mg every day or every other day (EOD). The suspension form has a slower release than the oral compound but is still administered frequently.

  • Medical Dosage (for HAE): Initial dose is typically 2 mg orally, three times a day. The maintenance dose is often decreased to 2 mg daily over time.


Half-Life and Detection Time

Parameter Value (Approximate) Detection Time (Approximate)
Half-Life (Oral) 4–5 hours 3 weeks (Urine)
Half-Life (Injectable) 24 hours 9 weeks (Urine)

Note on Detection Time: These times are estimates. The actual detection time depends heavily on the specific drug test (urine, blood, hair), individual metabolism, dosage, and duration of use. Stanozolol is metabolized into unique compounds (metabolites) that are detectable for a significant time after the parent drug is cleared, especially a primary metabolite called 3'-hydroxystanozolol. Hair tests can potentially detect use for up to 12 months.


Sterogenic, Progestrogenic, and Prolactin Effects

  • Estrogenic (Sterogenic) Effects:

    • Effect: Zero/None. Stanozolol is a DHT-derivative and cannot be converted into estrogen by the aromatase enzyme.

    • Clinical Relevance: Users do not experience estrogen-related side effects like gynecomastia or significant water retention.

  • Progestrogenic Effects:

    • Effect: Zero/None of significance. Stanozolol does not exhibit significant binding affinity for the progesterone receptor (PR).

    • Clinical Relevance: It is not associated with progesterone-related side effects.

  • Prolactin Effects:

    • Effect: Indirect/None. Stanozolol is not known to directly increase prolactin levels.

    • Clinical Relevance: Prolactin-related side effects (such as lactation/galactorrhea, often associated with compounds that are progestins) are not typical for Stanozolol use.


Anabolic Androgenic Ratio

The ratio is a comparison of the drug's anabolic (muscle-building) effects to its androgenic (masculinizing) effects, compared to testosterone (which is standardized at 100:100).

  • Anabolic Androgenic Ratio (Stanozolol): Approximately 300:30 to 300:100 (depending on the source and measurement method).

  • Simplified Digits (Ratio of Anabolic:Androgenic): 3:1 to 10:1 (e.g., 300 to 30 or 300 to 100). The most frequently cited raw figure in the scientific literature is 30:1.

  • The Number: 30:1

This ratio indicates that Stanozolol has a much higher potential for building tissue than for producing strong masculinizing side effects, though the androgenic effects are still significant, especially at high doses.

Pharmacological Properties

Half Life

9 hours

Active Dose

100%

Detection

1.87 days

Concentration

10 mg/tab

Anabolic/Androgenic Profile

Anabolic Rating320
Androgenic Rating30

Usage Effectiveness

Bulking
Cutting
Strength
Recomposition

Activity Profile

Estrogenic

None

Progestanic

None

Water Retention

None

Aromatization

No

Benefits

✓ Enhanced Muscle Definition ✓ Improved Strength Gains ✓ Reduced Water Retention ✓ Increased Endurance ✓ Increased Red Blood Cell Production

Dosage Recommendations

Beginner

20-40 mg/week

Intermediate

40-60 mg/week

Advanced

60-100 mg/week

Side Effects

Common

⚠ Acne ⚠ Oily Skin ⚠ Hair Loss (Male Pattern Baldness) ⚠ Reduced HDL Cholesterol ⚠ Testosterone Suppression ⚠ Joint Pain

Severe

⚠ Elevated Cholesterol (LDL) ⚠ Virilization (in females) ⚠ Liver Toxicity (Hepatotoxicity) ⚠ Elevated Liver Enzymes

Safety Information

Liver Toxicity

High

Kidney Toxicity

Low

Cardiovascular Risk

Moderate

Disclaimer: This information is for educational purposes only. Always consult with a qualified healthcare professional before using any compounds.