Methyl-1-Testosterone

Methyl-1-Testosterone (M1T), also known as methyldihydroboldenone, is a synthetic and orally active anabolic-androgenic steroid (AAS). It was never approved for medical use and is a controlled substance due to its potent effects. It's the 17α-methyl derivative of 1-testosterone.

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Benefits and Side Effects

Like other anabolic steroids, M1T can promote muscle growth and strength. However, these benefits come with significant risks, and it's important to note that the substance is on the World Anti-Doping Agency's prohibited list.

• Potential Benefits:

  • Significant increase in muscle mass and strength.

  • Improved athletic performance.

  • Enhanced recovery after exercise.

• Side Effects: M1T is a C17-alpha alkylated compound, which can be highly hepatotoxic (toxic to the liver). Side effects can include:

  • Liver toxicity: This is a major concern, especially with oral administration, and can lead to serious liver damage.

  • Cardiovascular issues: Increased risk of heart disease, stroke, and high blood pressure.

  • Androgenic side effects: Acne, hair loss (male pattern baldness), and increased body and facial hair growth.

  • Estrogenic and hormonal side effects: While M1T doesn't directly convert to estrogen, it can still cause hormonal imbalances, leading to gynecomastia (breast tissue growth in males), water retention, and testicular atrophy.

  • Mental and emotional changes: Mood swings, increased aggression, depression, and anxiety.

  • Suppression of natural testosterone production: Your body will stop producing its own testosterone, which can lead to fatigue and other withdrawal symptoms after use is discontinued.

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Pros and Cons

The pros and cons of M1T are a direct reflection of its benefits and side effects.

• Pros: Its main "pro" is its powerful ability to increase muscle mass and strength quickly, which is why it's used illicitly by some athletes and bodybuilders.

• Cons: The cons are substantial and outweigh the benefits for most people.

  • High toxicity: Severe liver and cardiovascular risks.

  • Legality and regulation: It's a controlled substance and is banned in competitive sports.

  • Hormonal disruption: Can lead to significant and long-lasting hormonal imbalances.

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Dosage and Frequency

There is no standard medical dosage for M1T since it was never approved for medical use. Doses used in research and illicit circles vary widely, but typically range from 5 mg to 30 mg per day. Due to its high toxicity, cycles are usually kept short, often only 2-4 weeks.

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Half-Life and Detection Time

• Half-life: The half-life of M1T is relatively short, likely a few hours. This means the compound is quickly metabolized by the body.

• Detection time: The detection time for M1T can vary depending on the testing method. While the parent compound is eliminated quickly, its metabolites can be detectable in urine for a longer period. Some studies suggest that metabolites can be detected for several weeks after a single dose.

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Sterogenic, Progestronic, and Prolactin Effects

• Sterogenic Effects: M1T is a potent anabolic steroid. It binds to the androgen receptor, which stimulates protein synthesis and muscle growth.

• Progestronic Effects: M1T does not have significant progestogenic activity. Unlike some other anabolic steroids, it doesn't directly bind to the progesterone receptor.

• Prolactin Effects: M1T does not have a direct effect on prolactin. However, some anabolic steroids can increase prolactin levels through various mechanisms, which can lead to gynecomastia and erectile dysfunction.

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Anabolic-Androgenic Ratio

The anabolic-androgenic ratio compares a steroid's ability to build muscle (anabolic) with its ability to cause masculine characteristics (androgenic). Testosterone is used as the baseline with a ratio of 100:100. M1T is known for having a very favorable anabolic-androgenic ratio, often cited as 1000:200. This means it is highly anabolic while being less androgenic than testosterone, although it still produces significant androgenic side effects.