Masteron Enanthate
Active Substance: Masteron Enanthate
Description
What is Masteron Enanthate?
Masteron Enanthate is a long-acting anabolic-androgenic steroid (AAS) that is a derivative of dihydrotestosterone (DHT). Its formal chemical name is drostanolone enanthate. The more common and historically significant form of this compound is Masteron Propionate (drostanolone propionate), which has a shorter ester and therefore a shorter half-life. Masteron Enanthate is essentially the same active steroid (drostanolone) but with a longer ester attached, which makes its effects last longer in the body.
Other Names
-
Drostanolone Enanthate
-
Dromostanolone Enanthate
-
2α-Methyl-5α-androstan-17β-ol-3-one 17β-enanthate
Benefits and Side Effects
Benefits:
-
Muscle Hardening and Definition: Masteron is highly valued by bodybuilders and athletes during "cutting" cycles. It's known for its ability to improve muscle hardness, density, and vascularity, which is often attributed to its anti-estrogenic properties and its lack of water retention.
-
Anti-Estrogenic Effects: As a DHT derivative, Masteron does not aromatize into estrogen. This means it doesn't cause common estrogen-related side effects like gynecomastia (male breast tissue enlargement) or water retention. It may also have some anti-estrogenic effects on its own, which can help to counteract the estrogenic effects of other steroids it's stacked with.
-
Increased Strength: While not a primary mass-building steroid, Masteron can contribute to notable increases in strength, which is beneficial for maintaining intensity during a calorie-restricted cutting phase.
-
Mild Side Effect Profile: Compared to many other anabolic steroids, Masteron is considered to have a relatively mild side effect profile, particularly regarding liver toxicity and cardiovascular strain.
Side Effects:
-
Androgenic Side Effects: Because Masteron is a DHT derivative, it carries a high risk of androgenic side effects. These include:
-
Acne and oily skin
-
Accelerated male pattern baldness (in genetically predisposed individuals)
-
Increased body and facial hair growth
-
Potential for prostate enlargement
-
-
Cardiovascular Strain: Like many AAS, Masteron can negatively impact cholesterol levels. It can lower HDL ("good") cholesterol and may increase LDL ("bad") cholesterol, leading to an increased risk of cardiovascular disease.
-
Virilization in Women: Due to its strong androgenic nature, women who use Masteron risk developing virilization symptoms, such as a deepened voice, clitoral enlargement, and increased body hair.
-
Testosterone Suppression: Like all AAS, Masteron will suppress the body's natural production of testosterone. A post-cycle therapy (PCT) is often required to help restore natural hormone function after a cycle.
Pros and Cons
Pros:
-
Excellent for achieving a "hard" and defined look.
-
Does not convert to estrogen, eliminating the risk of gynecomastia and water retention.
-
Helps preserve muscle mass during a calorie deficit.
-
Provides a noticeable boost in strength.
-
Minimal to no liver toxicity.
Cons:
-
High risk of androgenic side effects, especially for those prone to male pattern baldness.
-
Can negatively impact cholesterol levels and cardiovascular health.
-
Strongly suppressive of natural testosterone production.
-
Not an effective steroid for significant mass gains.
-
Illegal for non-medical use in many countries.
Dosage and Frequency
Dosages for Masteron Enanthate vary depending on the individual's goals and experience level. Due to its longer ester, it is typically injected less frequently than Masteron Propionate. A common dosage might be in the range of 400-600 mg per week, often split into two equal injections per week to maintain stable blood levels. However, it's crucial to understand that these are general figures from the bodybuilding community and should not be considered medical recommendations.
Half-Life and Detection Time
-
Half-Life: The half-life of Masteron Enanthate is approximately 5-6 days. This is significantly longer than Masteron Propionate, which has a half-life of around 2-3 days.
-
Detection Time: The detection time for Masteron Enanthate is generally long, often cited as 3 weeks or more. This is a critical factor for athletes subject to drug testing.
Sterogenic, Progestogenic, and Prolactin Effects
-
Sterogenic/Estrogenic Effects: As a derivative of DHT, drostanolone is not a substrate for the aromatase enzyme, meaning it cannot convert to estrogen. This is one of its primary characteristics and why it is used in cutting cycles to avoid water retention and gynecomastia.
-
Progestogenic Effects: Masteron is not known to have significant progestogenic activity. Unlike some other steroids (like nandrolone or trenbolone), it does not directly bind to the progesterone receptor.
-
Prolactin Effects: Masteron does not cause an increase in prolactin levels. This is another advantage for bodybuilders, as elevated prolactin can lead to side effects such as gynecomastia (in some cases) and sexual dysfunction.
Anabolic-Androgenic Ratio
The anabolic-androgenic ratio of drostanolone is 62:25. This ratio is based on a standard that compares a substance's anabolic (muscle-building) and androgenic (masculinizing) effects to those of testosterone, which is set at 100:100. The ratio indicates that drostanolone is less anabolic and significantly less androgenic than testosterone. However, it's important to note that this is a historical ratio based on older studies and may not perfectly reflect real-world effects, especially since Masteron is known to provide a hard, defined look that is highly valued in bodybuilding.
Pharmacological Properties
Half Life
5 days
Active Dose
70%
Detection
3.57 weeks
Concentration
250 mg/ml
Anabolic/Androgenic Profile
Usage Effectiveness
Activity Profile
Estrogenic
None
Progestanic
None
Water Retention
None
Aromatization
No
Benefits
Dosage Recommendations
Beginner
200-400 mg/week
Intermediate
400-600 mg/week
Advanced
600-800 mg/week
Evidence-based planning resources
Dive deeper into Masteron Enanthate cycle design, stacking options, and harm-reduction checklists available inside Anabolic Planner.
- Masteron Enanthate compound database overviewCompare Masteron Enanthate with other steroid agents in the structured compound index.
- Masteron Enanthate stack and cycle templatesReview evidence-based cycle outlines, dose progressions, and PCT pairings that incorporate Masteron Enanthate.
- Harm-reduction guide for Masteron EnanthateRefresh safety monitoring, lab work, and countermeasure strategies tailored for Masteron Enanthate protocols.
Peer-reviewed reference material
Validate mechanisms, contraindications, and regulatory guidance for Masteron Enanthate with trusted clinical databases.
- Masteron Enanthate clinical research on PubMedSearch peer-reviewed human and veterinary studies discussing efficacy, endocrine impact, and contraindications.
- Masteron Enanthate pharmacology via Drug Information PortalReview mechanisms, synonyms, regulatory status, and toxicology summaries from the U.S. National Library of Medicine.
Side Effects
Common
Severe
Safety Information
Liver Toxicity
None
Kidney Toxicity
Low
Cardiovascular Risk
Moderate
Disclaimer: This information is for educational purposes only. Always consult with a qualified healthcare professional before using any compounds.