Dimethyltrienolone

Dimethyltrienolone is an unmarketed, highly potent synthetic anabolic-androgenic steroid (AAS) that's orally active. It is also known by its developmental code name RU-2420 and chemical names like 7α,17α-dimethyltrenbolone and 7α,17α-dimethylestra-4,9,11-trien-17β-ol-3-one. It's a derivative of nandrolone and is considered to be one of the most potent AAS ever developed.

---

Side Effects and Benefits

As with all anabolic steroids, dimethyltrienolone presents a range of risks and potential side effects.

• Side Effects: Due to its extreme potency and 17α-alkylation, it is considered exceedingly hepatotoxic (toxic to the liver). It shares other common side effects of anabolic steroids, including but not limited to:

  • Androgenic effects: severe acne, male pattern baldness, and prostate stimulation.

  • Cardiovascular risks: harmful changes in cholesterol levels, high blood pressure, and left ventricular hypertrophy, which can lead to heart attack and stroke.

  • Hormonal disruptions: suppression of natural testosterone production, leading to testicular shrinkage and infertility in men. In women, it can cause masculinizing effects like a deepened voice and excessive body hair growth.

  • Psychological effects: mood swings, aggression ("roid rage"), and mania.

• Benefits: Dimethyltrienolone was never marketed for medical use, so its benefits are not clinically established. However, as an anabolic steroid, its potential benefits are similar to other AAS:

  • Increased muscle mass and strength: It promotes protein synthesis, leading to muscle growth.

  • Improved endurance: It can stimulate red blood cell production, which increases oxygen delivery to muscles.

  • Wasting syndrome treatment: Anabolic steroids can be used to treat muscle wasting conditions associated with chronic illnesses like cancer and AIDS.

---

Pros and Cons

 

• Pros: The primary "pro" of dimethyltrienolone is its extreme potency. It has a very high affinity for androgen and progesterone receptors, making it a powerful compound for building muscle and increasing strength. It also does not aromatize into estrogen, meaning it does not cause estrogenic side effects like gynecomastia.

• Cons: The most significant "con" is its extreme hepatotoxicity. The high risk of liver damage is a major reason it was never approved for medical use. It also carries all the other severe side effects associated with anabolic steroids, which can be irreversible and life-threatening. The lack of clinical data on humans also makes its use highly dangerous.

---

Dosage, Frequency, Half-Life, and Detection Time

There is no medically established or safe dosage for dimethyltrienolone because it was never approved for human use. Information regarding its dosage and frequency comes from anecdotal reports and black market use, which are unreliable and highly dangerous.

• Half-life and Detection Time: Information on the half-life and detection time of this specific steroid is not widely available. However, as an orally administered C17α-alkylated steroid, it would likely have a shorter half-life than injectable compounds. The detection time in drug tests is influenced by many factors, including dosage, frequency of use, and individual metabolism. Oral steroids typically have a detection window of 3-8 weeks, but this can vary.

---

Sterogenic, Progestogenic, and Prolactin Effects

• Anabolic-Androgenic Ratio: This ratio measures a steroid's anabolic (muscle-building) effects compared to its androgenic (masculinizing) effects. Dimethyltrienolone is an incredibly potent anabolic steroid, with studies in animals showing it has an anabolic potency of over 100 times that of methyltestosterone. Its androgenic potency is similarly high, at 100 times or more than methyltestosterone. Therefore, its anabolic-androgenic ratio is around 1:1.

• Progestogenic Effects: Dimethyltrienolone is an extremely potent agonist of the progesterone receptor (PR). This progestogenic activity can lead to side effects.

• Prolactin Effects: High levels of progestogenic activity can indirectly increase prolactin levels, a hormone that can cause side effects such as gynecomastia (enlarged male breasts) and sexual dysfunction. While dimethyltrienolone doesn't directly raise prolactin, its strong progestogenic nature can lead to an increase in prolactin-related side effects, particularly when stacked with other steroids.