DHB (Dihydroboldenone Cypionate)
Active Substance: DHB
Description
What is DHB (Dihydroboldenone Cypionate)?
Dihydroboldenone Cypionate, often referred to as DHB, is a synthetic anabolic-androgenic steroid (AAS). Its other names include 1-Testosterone and δ1-dihydrotestosterone (δ1-DHT). It is a derivative of dihydrotestosterone (DHT) and is closely related to the steroid boldenone (Equipoise). However, unlike boldenone, it is not a 5α-reduced compound. It is known for its high anabolic and androgenic potency. The Cypionate ester attached to the Dihydroboldenone compound makes it a long-acting injectable steroid, meaning it is released slowly into the bloodstream over time.
Side Effects and Benefits
Benefits:
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Muscle Growth (Anabolic Effects): DHB is known for its potent anabolic effects, which means it can promote significant muscle mass and strength gains. It's often favored by bodybuilders for its ability to produce lean, high-quality muscle gains.
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Increased Strength: Due to its powerful anabolic properties, users can experience a notable increase in physical strength.
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Lack of Estrogenic Activity: One of the key benefits of DHB is that it does not convert to estrogen (it is not a substrate for aromatase). This means it is less likely to cause side effects such as gynecomastia (development of breast tissue in men), water retention, and bloating, which are common with many other anabolic steroids.
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Hard, Defined Look: The absence of water retention can lead to a "hard" and defined appearance, which is desirable for bodybuilders, especially during cutting cycles.
Side Effects:
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Androgenic Side Effects: Despite a favorable anabolic-to-androgenic ratio, DHB can still cause androgenic side effects. These include:
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Acne
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Oily skin
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Accelerated hair loss in those predisposed to male pattern baldness
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Increased body and facial hair growth
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Cardiovascular Strain: Like many AAS, DHB can negatively impact cholesterol levels, potentially leading to an increase in LDL (bad cholesterol) and a decrease in HDL (good cholesterol), which increases the risk of cardiovascular disease.
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Suppression of Natural Testosterone: DHB will suppress the body's natural testosterone production. Post-cycle therapy (PCT) is typically required to help restore natural hormone levels after use.
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Hepatotoxicity: While not as liver-toxic as oral steroids, all steroids can put a strain on the liver, and liver function should be monitored.
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Mental and Emotional Changes: Users may experience mood swings, irritability, and aggression, often referred to as "roid rage."
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Pain at Injection Site: Due to its chemical structure, some users report significant pain and swelling at the injection site, a phenomenon sometimes referred to as "DHB Flu."
Pros and Cons
Pros:
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Powerful anabolic effects for significant muscle and strength gains.
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Does not aromatize into estrogen, eliminating the risk of gynecomastia and water retention.
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Can lead to a "hard" and vascular physique.
Cons:
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High potential for androgenic side effects.
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Pain and inflammation at the injection site can be a significant issue for some users.
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Can cause significant suppression of natural testosterone.
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Potential for negative cardiovascular and liver effects.
Dosage and Frequency
Information on specific dosages for performance-enhancing purposes is not officially approved and varies widely among users. However, based on anecdotal reports from bodybuilding and steroid-related forums, typical dosages for Dihydroboldenone Cypionate might range from 200-400 mg per week, administered through intramuscular injection.
The frequency of injections is influenced by the Cypionate ester, which provides a long half-life. Therefore, injections are often done once or twice per week to maintain stable blood levels.
Half-Life and Detection Time
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Half-Life: The half-life of Dihydroboldenone Cypionate is not precisely documented in medical literature, but because of its Cypionate ester, its half-life is estimated to be similar to that of testosterone cypionate, which is approximately 8 days. This means it takes about 8 days for half of the administered dose to be eliminated from the body.
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Detection Time: The detection time for injected anabolic steroids can be quite long. While there is no definitive, publicly available information for DHB, it is a long-ester steroid. Due to its chemical structure and the presence of the ester, it can be detected in drug tests for a prolonged period, often for several months after the last injection. Detection times can vary significantly based on individual metabolism, dosage, and the sensitivity of the drug test.
Sterogenic, Progestogenic, and Prolactin Affects
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Estrogenic Affects: DHB does not convert to estrogen, so it does not have any estrogenic effects. This is a major reason it is popular among users who want to avoid water retention and gynecomastia.
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Progestogenic Affects: DHB is a derivative of boldenone, which itself is a derivative of testosterone. It is not a progestin, and therefore, it is not known to have direct progestogenic activity.
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Prolactin Affects: While there are no direct scientific studies on DHB's specific effects on prolactin, some users of anabolic steroids, particularly those with progestogenic activity, can experience elevated prolactin levels. Since DHB is not a progestin, it is not expected to directly cause a significant increase in prolactin. However, some users report symptoms that might be associated with prolactin, but this is likely related to the use of other compounds stacked with DHB. Dihydrotestosterone (DHT), from which DHB is a derivative, has been shown in some studies to have an inhibitory effect on estrogen-induced prolactin release.
Anabolic-Androgenic Ratio
The anabolic-androgenic ratio is a measure of a steroid's anabolic (muscle-building) effects versus its androgenic (masculinizing) effects, compared to testosterone. Testosterone has a standard ratio of 100:100.
DHB has a very high anabolic-to-androgenic ratio. While exact figures vary and are often debated in the bodybuilding community, its anabolic rating is often cited as being 150-200 and its androgenic rating is around 50-80, based on animal studies. This would translate to a ratio of approximately
or .Pharmacological Properties
Half Life
8 days
Active Dose
69%
Detection
6.00 months
Concentration
250 mg/ml
Anabolic/Androgenic Profile
Usage Effectiveness
Activity Profile
Estrogenic
None
Progestanic
None
Water Retention
None
Aromatization
No
Benefits
Dosage Recommendations
Beginner
200-400 mg/week
Intermediate
400-600 mg/week
Advanced
600-800 mg/week
Evidence-based planning resources
Dive deeper into DHB (Dihydroboldenone Cypionate) cycle design, stacking options, and harm-reduction checklists available inside Anabolic Planner.
- DHB (Dihydroboldenone Cypionate) compound database overviewCompare DHB (Dihydroboldenone Cypionate) with other steroid agents in the structured compound index.
- DHB (Dihydroboldenone Cypionate) stack and cycle templatesReview evidence-based cycle outlines, dose progressions, and PCT pairings that incorporate DHB (Dihydroboldenone Cypionate).
- Harm-reduction guide for DHB (Dihydroboldenone Cypionate)Refresh safety monitoring, lab work, and countermeasure strategies tailored for DHB (Dihydroboldenone Cypionate) protocols.
Peer-reviewed reference material
Validate mechanisms, contraindications, and regulatory guidance for DHB (Dihydroboldenone Cypionate) with trusted clinical databases.
- DHB clinical research on PubMedSearch peer-reviewed human and veterinary studies discussing efficacy, endocrine impact, and contraindications.
- DHB pharmacology via Drug Information PortalReview mechanisms, synonyms, regulatory status, and toxicology summaries from the U.S. National Library of Medicine.
Side Effects
Common
Severe
Safety Information
Liver Toxicity
None
Kidney Toxicity
Low
Cardiovascular Risk
Moderate
Disclaimer: This information is for educational purposes only. Always consult with a qualified healthcare professional before using any compounds.