Genabol

Genabol, also known by its chemical name Norboletone, is a synthetic, orally active anabolic-androgenic steroid (AAS) that was never officially marketed for medical use. It was developed in the 1960s but was not commercially released due to concerns about its potential toxicity. Despite this, it gained notoriety in the early 2000s when it was identified in drug tests on athletes as part of the BALCO scandal.

Due to its nature as an unapproved and unmarketed substance, detailed, reliable information on its specific effects, pros, cons, and precise dosages is extremely limited and largely anecdotal. The following information is based on the general properties of anabolic-androgenic steroids and available reports on Norboletone.

Other Names

• Norboletone

• Norbolethone

Side Effects and Benefits

Like all anabolic steroids, Genabol would have both potential benefits and significant side effects. The benefits are typically sought for non-medical purposes, such as in sports and bodybuilding.

Potential Benefits (as an AAS):

• Increased Muscle Mass: Anabolic steroids promote protein synthesis, leading to muscle growth.

• Increased Strength: Users often experience a significant increase in muscular strength.

• Enhanced Recovery: AAS can help the body recover faster from intense workouts.

• Increased Red Blood Cell Production: This can improve oxygen delivery to muscles, enhancing endurance.

Side Effects (General to AAS, and likely for Genabol):

• Hepatotoxicity: As an oral steroid, it is likely to be C17-alpha alkylated, which can be very stressful on the liver and lead to liver damage, including liver tumors and blood-filled cysts (peliosis hepatis).

• Cardiovascular Issues: AAS can negatively impact cholesterol levels (decreasing HDL and increasing LDL), leading to an increased risk of high blood pressure, heart attack, and stroke.

• Hormonal Imbalances:

  • In men: Can lead to testicular atrophy (shrinking of the testicles), gynecomastia (enlarged breast tissue), decreased sperm production, and male-pattern baldness.

  • In women: Can cause virilization, including a deepened voice, clitoral enlargement, increased body hair, and male-pattern baldness. These effects can be irreversible.

• Psychological Effects: "Roid rage" (aggression, irritability), mood swings, mania, and depression.

• Acne and Oily Skin: AAS can increase sebum production.

• Stunted Growth: In adolescents, AAS can prematurely halt bone development.

Pros and Cons

Pros:

• Potentially significant increases in muscle mass and strength.

• Potential for improved athletic performance and recovery.

Cons:

• Severe health risks: The unmarketed nature of Genabol suggests it had significant, unmanageable toxicity concerns.

• Legal status: It is a banned substance in most sports and is often illegal to possess without a prescription.

• Lack of medical guidance: As it was never approved, there are no established medical guidelines for its use, making any use highly dangerous.

Dosage and Frequency

There are no medically established dosages or frequency for Genabol. Any information on this topic is based on illicit and unregulated use, which is highly risky and should be avoided.

Half-Life and Detection Time

Due to the lack of medical research, the half-life of Genabol is not officially documented. However, as an oral steroid, its half-life would likely be relatively short, similar to other oral AAS. The detection time in drug tests, however, is a different matter. "Designer" steroids like Norboletone were specifically created to be "undetectable" by traditional drug tests. However, advances in anti-doping technology have made it possible to detect these compounds, and they are now on the World Anti-Doping Agency's (WADA) list of prohibited substances. The detection window would depend on the specific testing method, but it could potentially be weeks or even months.

Sterogenic, Progestogenic, and Prolactin Affects

• Sterogenic: This term is not a standard pharmacological term. Anabolic-androgenic steroids are a class of steroids. Genabol is a steroidal androgen, meaning it is a synthetic version of androgens (male sex hormones).

• Progestogenic: Progestogenic activity refers to a compound's ability to activate the progesterone receptor. Some anabolic steroids, particularly those derived from nandrolone, have progestogenic effects. This can lead to increased prolactin levels and contribute to gynecomastia. While Norboletone is a nandrolone derivative, its specific progestogenic activity is not well-documented.

• Prolactin: Prolactin is a hormone associated with lactation and other functions. Some progestogenic steroids can increase prolactin levels, which can lead to side effects like gynecomastia and sexual dysfunction.

Anabolic Androgenic Ratio

The anabolic-androgenic ratio is a measure of a steroid's ability to promote muscle growth (anabolic effect) versus its ability to produce male sex characteristics (androgenic effect), with testosterone's ratio being 100:100. While a precise numerical ratio for Genabol is not widely available, designer steroids are often created to have a high anabolic-to-androgenic ratio, meaning they are intended to be more "anabolic" than "androgenic." However, it's crucial to understand that all anabolic steroids possess both properties, and an altered ratio does not eliminate the androgenic side effects.